Multi-Plate Conductor (MPC)
Hit the Right Notes
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Stratedigm’s patent-pending Multi-Plate Conductor (MPC) integrates advanced machine learning algorithms to revolutionize scheduling within the Stratedigm automation suite. By leveraging machine learning, MPC optimizes the sequencing of experiments across multiple plates, enhancing both time and resource management in complex protocols.
Optimization Through Machine Learning Algorithms
Traditional multi-plate experiments frequently encounter inefficiencies stemming from the sequential processing of tasks. For example, when a plate is incubating, subsequent steps are delayed until the incubation is completed. MPC recognizes these critical points and arranges for tasks to be executed in parallel. If future plates require liquid handling, MPC will run the incubation and liquid handling steps concurrently. Since these steps do not interfere with each other, MPC can optimize the process by handling multiple plates simultaneously. Moreover, MPC has the capability to adapt the experiment schedule dynamically by utilizing real-time data from each plate.
Key Features and Benefits
- Dynamic Resource Allocation: MPC continuously monitors the status of each plate and instrument module, allowing it to schedule tasks optimally. This adaptive scheduling reduces idle time and maximizes the use of resources.
- Parallel Execution Capability: Through machine learning-driven insights, MPC identifies opportunities for parallel execution of tasks across different plates and plate types. This capability significantly reduces the overall time required to complete multi-step assays.
- Flexible Experiment Setup: Researchers can easily configure experiments using various plate types (e.g., 96-well, 384-well) and run them concurrently. This flexibility not only enhances throughput but also accommodates diverse experimental requirements seamlessly.
Enhanced Efficiency and Accelerated Discoveries
MPC enables researchers to focus more on data analysis and interpretation rather than experimental logistics by minimizing wait times and maximizing concurrent processing. This efficiency gain translates into accelerated scientific discoveries and increased productivity in laboratory workflows.
Case Study: Improved Efficiency in Functional Assays
Using a Flow CAST® Basophil Activation Test (BAT), the Stratedigm team achieved a 30% reduction in additional processing time per plate when utilizing Multi-Plate Conductor. If conflicting plate needs are eliminated, up to a 90% reduction in additional processing time could be achieved.
Conducting Experiments with the Multi-Plate Conductor
1. Assemble Your Instruments
The minimum requirement to use MPC is a Stratedigm automation suite with an analyzer, A600, and A710. CellCapture will also need the Visual Protocol Designer upgrade to design the MPC templates.
2. Create a Score
Set up the Visual Protocol Designer for your experiment.
3. Rehearse the Performance
Run the VPD and MPC will learn the duration of each block in your experiment.
4. Let the Conductor Practice
Multi-Plate Conductor will optimize the schedule so there is minimal downtime with the different instruments and time is used effectively.
5. Enjoy the Dynamic Tempo
Multi-Plate Conductor can run the experiment and adjust the schedule depending on the conditions that are set for the experiment and the results during the performance.